凤眼草化学成分的分离与鉴定  

Isolation and identification of chemical constituents from the fruits of Ailanthus altissima(Mill.)Swingle

作　　者：赵春超[1] 邵建华[1] 张玉伟[2] 曹丹丹[1] 王金辉[2] 李铣[2] 

机构地区：[1]扬州大学生物科学与技术学院,江苏扬州225009 [2]沈阳药科大学中药学院,辽宁沈阳110016

出　　处：《沈阳药科大学学报》2009年第10期800-802,806,共4页Journal of Shenyang Pharmaceutical University

摘　　要：目的对凤眼草的质量分数95%乙醇提取物进行分离并鉴定。方法采用硅胶柱色谱、聚酰胺柱色谱等方法分离纯化,1H-NMR、13C-NMR等方法进行结构鉴定。结果分离得到5个黄酮类化合物,分别鉴定为kaempferol（1）、quercetin（2）、kaempferol3,7-O-bis-α-L-rhamnopyranoside（3）、kaempferol-3-O-α-L-arabinofuranosyl-7-O-α-L-rhamnopyranoside（4）、quercetin3-O-β-D-glucopyrano-side（5）。结论化合物3~5为首次从臭椿属植物中分离得到。Objective To study the chemical constituents from the 95% EtOH extract of the fruits of Ailanthus al tissima（ Mill. ）Swingle. Methods The constituents were isolated by silica gel column chromatography and polyamide column chromatography, and the ^1H-NMR, ^13C-NMR spectroscopic analysis were employed for the structural elucidation. Results Compounds 1-5 were obtained and their structures were identified as kaempferol （ 1 ）, quercetin （2）, kaempferol 3,7- O-bis-α-L-rhamnopyranoside （ 3 ）, kaempferol-3-O-α-L-arabi- nofuranosyl-7-O-a-L-rhanmopyranoside （ 4 ）, quercetin 3-O-β-D-glucopyranoside （ 5 ）. Conclusions Among them, compounds 3-5 are isolated from this genus for the first time.

关 键 词：臭椿 果实 化学成分 结构鉴定 

分 类 号：R914[医药卫生—药物化学] R932[医药卫生—药学]