胰腺癌早期诊断分析  

Analysing early diagnosis of pancreatic cancer

作　　者：胡海燕[1] 刘颂[1] 苑凤昌[1] 葛杰[1] 林宇[1] 高庆林[1] 李国华[1] 

机构地区：[1]齐齐哈尔医学院第一附属医院,齐齐哈尔161041

出　　处：《中国医药导报》2009年第36期167-168,共2页China Medical Herald

基　　金：黑龙江省教育厅科学技术研究资助项目(11521326)

摘　　要：目的:探讨提高胰腺癌早期诊断率的有效手段。方法:分析我院22例行根治性手术患者临床表现、胰腺CT及血清CA19-9水平、粪便K-ras、p53突变在胰腺癌早期诊断中的地位和作用。结果:行根治性手术22例,CT检查阳性19例(86.4%);CA19-9诊断18例(81.8%);粪便K-ras以及p53基因突变率分别为81.8%、77.3%。结论:重视胰腺癌的早期临床表现,借助胰腺CT及血清CA19-9水平、粪便K-ras、p53突变结果,可提高胰腺癌的早期诊断率。Objective：To investigate the effective means of improving the diagnosis rate of early pancreatic cancer. Meth-ods：Analysed routine clinical manifestations,pancreas CT and CA19-9 levels in serum,fecal K-ras,p53 mutations of 22 pancreatic cancer patients with radical surgery in the early diagnosis of the status and role. Results：Radical surgery was 22 cases,CT examination was 19 cases （86.4%）; CA19-9 diagnosis rate was 18 cases （81.8%）; fecal K-ras and p53 gene mutation rates separately were 81.8% and 77.3%. Conclusion：The importance of early clinical manifestation of pancreatic cancer,pancreas with CT and CA19-9 levels in serum,fecal K-ras,p53 mutations result,can increase the rate of early diagnosis of pancreatic cancer.

关 键 词：胰腺癌 早期诊断 CT 血清CA19-9 基因突变 

分 类 号：R735[医药卫生—肿瘤]