EEG特征在特发性癫痫诊治中的作用  

Effect of EEG features for diagnosis and treatment in idiopathic generalized epilepsy

作　　者：李清燕[1] 丁华瑛[1] 

机构地区：[1]四川省自贡市第五人民医院综合科,四川自贡643000

出　　处：《中国现代医学杂志》2009年第18期2847-2849,共3页China Journal of Modern Medicine

摘　　要：目的探讨EEG在特发性癫痫的诊断和治疗中的作用。方法回顾性分析80例特发性癫痫患者的临床和常规EEG特征。10例患者诊断为青少年肌痉挛癫痫(JME),35例患者有失神发作(AE),28例患者为全面强直痉挛发作(TCS),7例患者为成年期起病的特发性全面性癫痫(AIGE)。EEG分为典型(同步全面棘波或多棘波发放)、不典型(明显的局灶性或不对称)和正常。结果193个EEG当中,80例患者第1次EEG正常为45%,仅有33%发现典型异常。与其他类型相比,失神发作典型异常比例更高,需要更少的检测次数即可发现典型异常。对TCS和AIGE连续EEG出现更高比例的正常和非典型异常EEG结果。结论IGE患者应该根据临床病史选择恰当的治疗方法,因为等待一次典型的异常EEG会在正确诊断和治疗这些患者上导致不可接受的延误。[ Objective ] To explore the EEG and its contribution for diagnosis and management in a group of patients with a clinical diagnosis of idiopathic generalized epilepsy （IGE）. [ Methods ] We retrospectively studied clinical and EEG features of 80 patients with IGE. Ten patients were diagnosed with juvenile myoclonic epilepsy （JME）, 35 has absence epilepsy （AE）, 28 had generalized tonic clonic seizure, and 7 had adult-onset idiopathic generalized epilepsy （AIGE）. The EEG were classified in typical,atypical and normal. [Results] The 193 EEG exams were analyzed. The first EEG was normal in 45% of the 80 patients, and only 33% had typical abnormalities. AE had a higher proportion of typical examinations and needed fewer sequential examinations to register a typical abnormality compared with the other groups. By contrast, the serial EEG profile of TCS and AIGE showed a higher proportion of normal and atypical EEG findings. [ Conclusions ] IGE patients should be treated with appropriate therapy based on clinical history. Waiting for a typical abnormal EEG pattern can generate an unacceptable delay in the correct diagnosis and treatment of these patients may be difficult.

关 键 词：特发性癫痫 EEG 诊断 

分 类 号：R742.1[医药卫生—神经病学与精神病学]