鹰嘴豆种子水煎剂对高脂血症大鼠血脂含量影响的实验研究  

Experimental Study on Hypolipidemic Effect of Water Decoction of Chickpea Seeds in Rats

作　　者：田春元[1] 周秀佳[2] 

机构地区：[1]孝感学院生命科学技术学院,湖北孝感432000 [2]上海中医药大学中药学院,上海201203

出　　处：《食品科学》2010年第1期232-234,共3页Food Science

摘　　要：目的:考察鹰嘴豆种子水煎剂对高脂饲料致大鼠高脂血症血脂含量的影响。方法:取雄性SD大鼠,随机分组。除正常对照组饲喂正常饲料外,其余各组实验全程均饲喂高脂饲料。分别测定饲喂高脂饲料10d及灌胃鹰嘴豆种子水煎剂4周、6周后的血脂含量。结果:给药4～6周后,TC、LDL-C、TG降低,HDL-C、载脂蛋白AI升高,高剂量组的效果更明显。结论:鹰嘴豆种子水煎剂对高脂饲料致高脂血症大鼠的血脂水平有较好的调节作用。SD male rats were used as experimental animals to investigate whether water decoction of chickpea seeds（WDCS） has hypolipidemic effect.Seventy-two rats were randomly divided into 6 groups of 12 rats each.Rats fed normal diet were served as normal control group and all other groups were fed high fat diet over the whole experimental period.Blood lipid level in rats was assayed after 10 d of high fat diet feeding and 4 weeks and 6 weeks of continuous WDCS administration by gavage.Results showed that WDCS resulted in a decrease in rat serum TC,LDL-C and TG and an increase in HDL-C and APO AI and more significant changes in these blood lipid parameters were observed in high dose administered rats.Therefore,WDCS has a good regulatory effect on blood lipid level in hyperlipidemic rats.

关 键 词：鹰嘴豆 鹰嘴豆种子水煎剂 高脂血症 降血脂作用 

分 类 号：R286.26[医药卫生—中药学]