藿香正气水气相色谱指纹图谱特性研究  

GC fingerprint characteristics of Huoxiang Zhengqi Solution

作　　者：李红梅[1] 茹鑫[1] 梁悦[1] 王璐[1] 于爱民[1] 张寒琦[1] 师宇华[1] 

机构地区：[1]吉林大学化学学院,吉林长春130012

出　　处：《中成药》2010年第1期6-10,共5页Chinese Traditional Patent Medicine

摘　　要：目的:建立藿香正气水的GC指纹图谱。方法:采用水蒸气蒸馏和正己烷萃取藿香正气水,以正十七烷为参照物经毛细管气相色谱柱(含FID检测器)进行了分析。结果:对10批次藿香正气水供试品进行检测,建立了该药品的GC指纹图谱并标示了16个共有指纹峰。各共有峰相对保留时间变化的RSD均在0.5%以内。结论:该方法准确、重现性好,为进一步质量标准化研究和控制提供依据。AIM： To establish the GC fingerprint of Huoxiang Zhengqi Solution. METHODS： The volatile constituents of Huoxiang Zhengqi Solution were analyzed by capillary GC with FID detector using hydrodistillation and hexane extraction under n-heptadecane used as the reference substance. RESULTS： GC fingerprint of Huox- iang Zhengqi Solution, 16 common peaks were established on the basis of systematic methodology after 10 batches of samples were tested. Variation in the relative retention time of 16 identified common peaks were within 0.5% range. CONCLUSION： The analytical method for Huoxiang Zhengqi Solution is precise and reliable. The research would be helpful to offer an effective pattern for quality control of Huoxiang Zhengqi Solution.

关 键 词：藿香正气水 指纹图谱 GC 挥发性成分 

分 类 号：R927.1[医药卫生—药学]