198例异常孕产史者染色体核型分析  

Analysis on chromosomal karyotype of 198 cases with abnormal pregnancy-labor history

作　　者：阚珣[1] 杨剑丽[2] 温得中[2] 

机构地区：[1]辽宁省沈阳市妇幼保健所,110032 [2]吉林大学白求恩医学院遗传学系

出　　处：《中国妇幼保健》2010年第4期521-522,共2页Maternal and Child Health Care of China

基　　金：吉林省长春市科技计划项目(08SF55)资助项目

摘　　要：目的:通过对198例异常孕产史患者的外周血染色体检查,探讨染色体畸变与异常孕产史的关系。方法:采用人外周血淋巴细胞培养,常规G显带。结果:发现异常核型21例,异常检出率达10.61%。结论:染色畸变是导致异常孕产史的一个重要因素。Objective： To explore the relationship between abnormal chromosome karyotype and abnormal pregnancy - labor history by chromosomal detection of peripheral blood in 198 cases with abnormal pregnancy -labor history. Methods： Human peripheral blood lymphocyte culture and G - dominance band were used in the study. Results： The detection rate of abnormal chromosomal karyotype was 10. 61% （21 cases） . Conclusion： Chromosomal abnormality is an important inducing factor of abnormal pregnancy -labor history.

关 键 词：异常孕产史 染色体畸变 核型 G显带 

分 类 号：R394[医药卫生—医学遗传学]