蜂蛹富肽蛋白粉对大鼠免疫功能和血糖、血脂的影响  

Effect of Honeybee Pupae Peptide-rich Protein Powder on Immune Function, Blood Glucose and Blood Lipid in Rats

作　　者：盛晟[1] 周杰[1] 沈咏舟[1] 张佳[1] 朱枫桥[1] 

机构地区：[1]安徽农业大学动物科技学院,安徽合肥230036

出　　处：《食品科学》2010年第3期250-252,共3页Food Science

基　　金：合肥市科技计划项目(合科[2007]15号)

摘　　要：选用50只3周龄SD大鼠随机分成两组,分别灌喂蜂蛹蛋白粉和经消化酶水解的蜂蛹蛋白即富肽蛋白粉4周。结果表明,灌喂富肽蛋白粉可显著增加大鼠血清IgG、IgA含量和脾脏指数(P<0.05),对大鼠血清IgM和胸腺指数的影响无统计学意义。灌喂富肽蛋白粉可极显著降低大鼠血糖(GLU)含量(P<0.01),显著提高血清甘油三酯(TG)、血清高密度胆固醇(HDL-C)含量,降低血清低密度胆固醇(LDL-C)含量(P<0.05),而对血清游离脂肪酸(FFA)和总胆固醇(TC)含量影响不显著。结果提示,富肽蛋白粉可增强大鼠的免疫功能、降低血糖,并能够预防和减轻动脉粥样硬化的发生。Fifty 3-week-old SD rats were selected and randomly divided into 2 groups,namely treatment and control groups administered honeybee pupae peptide-rich protein powder and honeybee pupae protein powder for 4 consecutive weeks.Results showed that the contents of serum IgG,IgA and spleen index of rats treated with peptide-rich protein powder exhibited a significant increase（P〈0.05）,whereas no effect on serum IgM content and thymus index.In addition,compared with the control group,an extremely significant decrease in blood glucose（P〈 0.01）,a significant decrease in density lipoprotein cholesterol（LDL-C） content（P 〈0.05）,and an increase in serum triglyceride（TG） content and density lipoprotein cholesterol（HDL-C） content（P〈 0.05） were observed in rats treated with peptide-rich protein powder.However,peptide-rich protein powder had no significant effect on the contents of serum free fatty acids（FFA） and serum total cholesterol（TC）.Therefore,peptide-rich protein powder can enhance immune function,decrease blood glucose,and prevent the occurrence of atherosclerosis.

关 键 词：蜂蛹 富肽蛋白粉 大鼠 免疫功能 血糖 血脂 

分 类 号：R151.2[医药卫生—营养与食品卫生学]