猪骨羟基磷灰石的结构稳定性  

STRUCTURE PROPERTIES AND STABILITY OF THE PIG BONE HYDROXYAPATIE

作　　者：王大志[1] 杨兰 罗毅 黄允兰 张万群 汤洪高[1] 王会信[2] 刘凯[3] 陶菁 

机构地区：[1]中国科学技术大学材料科学与工程系 [2]中国军事医学科学院基础医学研究所 [3]安徽医科大学口腔系

出　　处：《生物物理学报》1998年第4期604-608,共5页Acta Biophysica Sinica

基　　金：国家自然科学基金

摘　　要：在不同酸碱条件下对猪骨处理，利用转靶Ｘ射线衍射（ＸＲＤ）、红外吸收（ＩＲ）、差热分析（ＤＴＡ）分别对猪骨的物相和微结构进行了分析，并与纯的羟基磷灰石（ＨＡ）进行了比较，研究了猪骨中纳米羟基磷灰石的结构稳定性。实验表明猪骨在弱酸弱碱溶液中羟基磷灰石相是稳定的，但晶粒尺寸、结晶度和非晶含量有所变化。６００°Ｃ的高温处理，可改善其结晶度。In this paper, we trcated the pia bones in different acidic and basic solutions.X-raydiffaction (XRD), infrared (IR) spectroscopy and DTA were emploved to analyse the phase composition and structure. The pig bones were compared with the pure HA which was prepered by wet chemical method to studty the structure properties and stability of the bones. This study provides further basis for the use of natural bones as bone implants. It showed that in weak acid and weak base the pig bone hydroxyapatite was stable, but the size of the grain, crystalinity and the amount of the amorphous changed. We also found that after sintering under 600°C,the crystallinity of the bones was improved. This is of graet importance to the development of the new prosthetic materials.

关 键 词：猪骨 羟基磷灰石 结构特点 稳定性 

分 类 号：R783.1[医药卫生—口腔医学] R318.08[医药卫生—临床医学]