油茶皂素毒性研究(Ⅲ)——油茶皂素对昆明种小鼠的致突变试验  

The Poisonous Study (Ⅲ )——the Causing Mutation Test of Sasanglla Saponin to Kunming Species Small Mouse

作　　者：胡绍海[1,2] 胡卫军[1,2] 许莲瑛 张乐书 李清明 陈裕旭 李军 

机构地区：[1]湖南师范大学生物系 [2]湖南省劳动卫生职业病防治研究所

出　　处：《中国油脂》1998年第6期57-58,共2页China Oils and Fats

摘　　要：报道了用乙醇法从油茶饼粕中提取的油茶皂素干粉（其含量＞８５％），对昆明种小鼠进行了致突变试验。经常规Ａｍｅｓ试验、骨髓ＰＣＥ微核试验和精子畸形试验，其研究结果三项试验均为阴性，可初步确认油茶皂素无致突变作用。This paper reports the causing mutation experiment of sasanglla Saponin powder (which containous is >85% and is extracted from sasanglla cake with alcohol) to kunming species small mouse. The results of regular ames test,marrow PCE minute nucleus test and sperm deformity test all are negative, so we can preliminarily affirm that sasanglla saponin has no mutation effect.

关 键 词：油茶皂素 小鼠 精子畸形 致突变试验 毒性 

分 类 号：R996.2[医药卫生—毒理学]