13例青少年起病的男性垂体催乳素瘤临床分析  

Clinical analysis of 13 adolescent onset male prolactinoma

作　　者：徐剑[1] 钟历勇[1] 张春芳[1] 范虹[1] 李征[1] 郭莹[1] 马于堃[1] 

机构地区：[1]首都医科大学附属北京天坛医院内分泌科,北京100050

出　　处：《临床内科杂志》2010年第4期258-260,共3页Journal of Clinical Internal Medicine

摘　　要：目的探讨男性青少年催乳素瘤的临床特点、治疗与预后。方法回顾性分析13例青少年男性催乳素瘤患者临床表现及疗效。结果（1）男性青少年催乳素瘤以大腺瘤为主。头痛和第二性征发育障碍常见，但较少引起生长停滞。（2）溴隐亭治疗安全有效，与手术相比，可以保护垂体前叶功能，改善第二性征发育。结论男性青少年催乳素瘤采用溴隐亭治疗较手术更为可取，必要时，联合治疗有助于缓解病情。Objective To investigate the clinical characteristics, therapies and prognosis of male adolescent patients with prolactinoma. Methods Retrospectively analyzed the clinical manifestation and therapeutic effect of 13 male adolescent patients with prolactinoma. Results （1）There was a predominance of maeroprolaetinomas in male adolescents. Headache and delay of pubertal development were the frequent symptoms whereas delay of growth was rarely observed. （2）Medical treatment with bromocriptine is effective and safe, compared with surgery it can preserve the anterior pituitary function and improve the pubertal development. Conclusions Bromocriptine is preferable to surgery in the treatment of prolactinoma in male adolescents, If necessary adjuvant therapy is helpful to improve the state of the illness

关 键 词：男性 青少年 催乳素瘤 

分 类 号：R736.4[医药卫生—肿瘤]