遗传性乳腺癌-卵巢癌临床分析  

Clinical analyse of hereditary breast-ovarian cancer syndrome

作　　者：乔丽雅[1] 王振国[1] 张江琴[1] 范敏[1] 成争先[1] 

机构地区：[1]解放军第309医院妇产科,北京100091

出　　处：《中国优生与遗传杂志》2010年第5期135-136,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨遗传性乳腺癌-卵巢癌的遗传学、诊断及诊疗,为其早期诊断及正确治疗提供依据。方法总结遗传性乳腺癌-卵巢癌患者的临床资料,对其遗传学、早期诊断及治疗等方面进行探讨。结果遗传性乳腺癌-卵巢癌起源于甲状腺滤泡上皮细胞,它单独发生或作为家族性肿瘤综合征发生。多发性病灶和同时伴发腺瘤性甲状腺肿是其特征性临床表现,并且多发生在年轻人;合理的手术治疗可以取得满意的疗效。结论遗传性乳腺癌-卵巢癌是一种遗传性疾病,早期诊断、合理的手术治疗可以取得满意的疗效。患者家族成员应长期随访。Objective ： To investigate the genetics and dignosis and treatment of hereditary breast - ovarian cancer syndrome in order to provide basis for its early diagnosis and treatment. Methods： We summarized the clinical data of hereditary breast - ovarian cancer syndrome, and combined with literature to investigate its etiology, early diagnosis and treatment. Results： Hereditary breast - ovarian cancer syndrome come of thyroid follicle epithelia cell, and mostly is young blood ; Reasonable operation can get satisfactory result in the treatment for hereditary breast - ovarian cancer syndrome. Conclutions ： HBOC is a kind of hereditary diseases ; there is satisfactory result when early diagnosis and reasonable operation are applied. Follow - up survey of family members should be per- formed in a long period of time.

关 键 词：遗传性乳腺癌-卵巢癌 遗传学 诊断 治疗 

分 类 号：R737.9[医药卫生—肿瘤] R737.31[医药卫生—临床医学]