α_1抗胰蛋白酶遗传类型在七个民族中的分布  

DISTRIBUTION OF a_1-AT PHENOTYPES IN SEVEN CHINESENATIONAL POPULATIONS

作　　者：于世辉[1] 张贵寅[1] 陈立男[1] 段玉芹[1] 赵会全[1] 黄承滨[1] 

机构地区：[1]哈尔滨医科大学医学遗传研究室

出　　处：《人类学学报》1990年第1期81-85,共5页Acta Anthropologica Sinica

基　　金：国家自然科学基金资助课题

摘　　要：调查了α_1-AT遗传类型在东北及内蒙古地区汉、蒙、朝鲜、满、达斡尔、鄂温克、鄂伦春等七个民族中的分布。计算了每个群体中的α_1-AT基因频率,经X^2检测证明七个群体α_1-AT表型分布均符合Hardy-weinberg法则。同时,将各少数民族人群α_1-ATM类型及变异型的基因频率与汉族人群进行了比较。The phenotypes of a1-AT were determinded for Chinese Han and six Chinese national minorities including Mongolian, Korean, Manchurian, Tahur, Owenkand Olunchun nationalities. The frequencies of PiM and Pivariant alleles were not significantly different between Han population and these national minorities. pitokyo allele is the most common a1-AT variant and Piz is absent in all the Chinese population observed by us, and one heterozygote was found in Olunchun nationality, showing certain evidence for studying the ties of blood between Chinese Han population and these Chinese national minorities.

关 键 词：抗胰蛋白酶 遗传型 民族 多态性 

分 类 号：Q987[生物学—遗传学]