无水乙醇局部消融治疗术后复发嗜铬细胞瘤  

Local absolute alcohol ablation for the treatment of recurrent pheochromocytoma

作　　者：尚鸣异[1] 王培军[1] 陆影[1] 马骏[1] 唐俊军[1] 席芊[1] 黄宗良[1] 高晓龙[1] 

机构地区：[1]上海同济大学附属同济医院放射科,200060

出　　处：《介入放射学杂志》2010年第5期373-375,共3页Journal of Interventional Radiology

摘　　要：目的评价CT引导下局部注射无水乙醇对术后复发性嗜铬细胞瘤的治疗效果。方法 5例嗜铬细胞瘤手术治疗后复发,其中右侧3例,左侧1例,双侧1例,手术病理为良性嗜铬细胞瘤,均在CT引导下行局部无水乙醇消融治疗。结果治疗后30dCT复查5例肿瘤均有不同程度缩小,所有病例已随访9～42个月,患者血压一直正常,未再发阵发性头晕、头痛及发作性晕厥等症状。尿香草扁桃酸正常。结论 CT引导下局部无水乙醇消融疗法治疗术后复发嗜铬细胞瘤,疗效确切且安全可靠,是非常具有临床价值的治疗手段。Objective to assess the clinical value of local injection of absolute alcohol under CT guidance in treating recurrent pheochromocytoma. Methods Five patients with benign recurrent pheochromocytoma were enrolled in this study. Of the five cases, the lesions were located on the right side in three, on the left in one and on both sides in one. All the lesions were pathologically proved to be benign ones. Under CT guidance the ablation therapy with local injection of absolute alcohol was performed. The therapeutic results were observed and evaluated. Results Thirty days after the treatment, different degrees of decrease in tumor size was observed on follow-up CT scans. All the patients were followed up for 9-42 months. During the follow-up period, both the blood pressure and the vanillyl mandelic acid （VMA） level in urine remained normal and no paroxysmal dizziness, headache or syncope occurred in all patients. Conclusion For the treatment of recurrent pheochromocytoma the ablation therapy by using local injection of absolute alcohol under CT guidance is a safe and practical therapeutic means with definite and reliable effectiveness.

关 键 词：嗜铬细胞瘤 复发 无水乙醇 消融 CT 

分 类 号：R736.6[医药卫生—肿瘤]