He-Ne激光照射对SP2/0骨髓瘤小鼠TNF及TNFR水平的影响  

Study of Effect of He Ne Laser Irradiation on TNF and TNFR Express Function in Mice with SP2/0 Marrow Tumour

作　　者：高美华[1] 冯献启[1] 宫照龙[1] 王海燕[1] 胡涛[1] 

机构地区：[1]滨州医学院免疫室

出　　处：《中国激光》1999年第3期269-272,共4页Chinese Journal of Lasers

基　　金：山东省教委资助项目

摘　　要：采用２４ｍＷＨｅ－Ｎｅ激光照射器照射荷瘤小鼠瘤区，观察激光照射对瘤鼠瘤组织内肿瘤坏死因子（ＴＮＦ）及肿瘤坏死因子受体（ＴＮＦＲ）的影响，结果表明激光照射组小鼠瘤体内ＴＮＦ活性明显增强，ＴＮＦＲ表达量增多，瘤细胞增殖率降低，与非激光组相比，有高度显著性差异（Ｐ＜０．０１）。A 24 mW He Ne laser irradiation was applied to the spleen region to observe the changes in levels of the tumour necrosis factor (TNF) and TNF receptor (TNFR) in mice with tumour. The results showed that TNF and TNFR were significantly higher in both of laser groups than control groups. It indicated that He Ne laser not only enhances the level of TNF but also promotes the expression of TNFR.

关 键 词：TNF TNFR 骨髓瘤 氦氖激光照射 激光治疗 

分 类 号：R730.57[医药卫生—肿瘤] R733.305[医药卫生—临床医学]