DLK1与肿瘤的关系  

DLK1 and neoplasms

作　　者：张艳丽[1] 康凯夫[2] 

机构地区：[1]广东医学院病理学系,广东湛江524023 [2]南方医科大学附属顺德第一人民医院病理科,广东佛山528300

出　　处：《国际病理科学与临床杂志》2010年第3期251-254,共4页Journal of International Pathology and Clinical Medicine

摘　　要：DLK1(delta drosophila homolog-like 1或delta-like 1 homologue)是表皮生长因子(EGF)家族成员之一,作为细胞分化调节的重要因子,DLK1具有广泛的生物学功能。近年来研究证实DLK1在许多肿瘤组织中高表达,通过多种机制参与肿瘤的发生、发展。Delta drosophila homolog-like 1（DLK1） is a member of the epidermal growth factor family.As an important factor in regulation of cell differentiation,DLK1 has a wide rang of biological functions.Recently,many studies have shown that the expression of DLK1 is up-regulated in many tumor tissues,which may be involved in the occurrence and development of neoplasms through a variety of mechanisms.

关 键 词：DELTA DROSOPHILA homolog-like1 肿瘤 基因 

分 类 号：R730.2[医药卫生—肿瘤]