碳纳米管与生物分子的相互作用  

Interactions between Carbon Nanotubes and Biomolecules

作　　者：鞠思婷[1] 朴玲钰[1] 杨磊[1] 刘祥志[1] 张天慧[1] 李忠军[1] 

机构地区：[1]国家纳米科学中心,北京100190

出　　处：《化学进展》2010年第9期1767-1775,共9页Progress in Chemistry

基　　金：国家自然科学基金项目(No.50602008);科技部重大研究计划项目(No.2006CB932600);中科院方向性项目(No.KJCX-YW-M03)资助

摘　　要：碳纳米管是一种具有特殊结构和性质的新型一维纳米材料,在生物学和临床医学上已有许多应用研究。大量研究表明,碳纳米管在药物载体、医学成像、疾病检测等方面有广泛的应用前景。碳纳米管与生物分子相互作用的机理和形式也成为目前研究的热门方向。本文总结了近几年来碳纳米管与氨基酸、多肽、蛋白质、酶、DNA等多种生物分子之间的相互作用,并对碳纳米管的生物学效应进行了综述。As a kind of one-demensional materials with special structure and properties, carbon nanotubes provide a wider prospect for the development of drug delivery system, medical imaging, and disease detection. The research on the specific mechanisms and forms of interactions between carbon nanotubes and biomolecules kave also become popular. This article puts forward a summarization of the latest research progress on the interactions between carbon nanotubes and various biological molecules, such as amino acids, peptides, proteins, enzymes and DNA. The progressive directions of biological distribution and toxicity of carbon nanotubes are also prospected.

关 键 词：碳纳米管 氨基酸 多肽 蛋白质 DNA 生物传感器 生物学效应 

分 类 号：O629[理学—有机化学] TB383[理学—化学]