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作 者:崔蓉 李平华[3] 李家菊 李川海 杨皓 傅新云 马明福
机构地区:[1]重庆市人口和计划生育科学技术研究院 [2]重庆市出生缺陷与生殖健康重点实验室,400020 [3]重庆医科大学附属第一医院
出 处:《中国计划生育学杂志》2010年第10期616-618,共3页Chinese Journal of Family Planning
基 金:重庆市科委攻关项目(编号:CSTC.2008AC0039)
摘 要:目的:了解要求再生育家庭眼病患儿疾病种类及病因,为预防其发生提供依据。方法:收集重庆市要求再生育家庭眼病患儿808例临床资料进行分析。结果:盲148例(18.32%),其中眼外伤致盲48例(32.43%)。眼遗传病626例(77.48%),其中单基因遗传病256例(40.89%);多基因遗传病370例(59.11%)。非遗传性眼病182例(22.52%),以后天性眼病(87.36%)为主,其中眼外伤占43.40%。结论:要求再生育家庭眼病患儿以遗传性眼病为主,但眼外伤是致盲的主要原因,应加强其预防。Objective:To understand and analyze the categories and causes of ophthalmopathy of the disabled children from the families applying for having another child in Chongqing so as to offer a clinical reference to reduction of blindness and visual impairment.Methods:Comprehensive analysis of the clinical data,based on 808 cases of ophthalmopathy of disabled children in Chongqing,was conducted.Results:There were 148 patients of blindness(18.32%),48(32.43%) due to ocular trauma.The hereditary and non hereditary diseases occurred in 626(77.48%) and 182(22.52%) patients,respectively.The former included single-gene genetic diseases(256 patients,40.89%) and polygene genetic disease(370 patients,59.11%).The latter mainly included acquired eye diseases(159 patients,87.36%),and 69(43.40%) caused by ocular trauma.Conclusion:The hereditary ophthalmopathy is a major type of disease,but ocular trauma is the main cause of blindness.So precaution should be strengthened.
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