奥扎格雷钠联合巴曲酶治疗进展性脑梗死的疗效观察  

作　　者：赵岐[1] 王红艳[2] 

机构地区：[1]吉林省通化市人民医院神经内科,134001 [2]北华大学附属医院神经内科,132011

出　　处：《当代医学》2010年第32期32-33,共2页Contemporary Medicine

摘　　要：目的评价奥扎格雷钠联合巴曲酶治疗进展性脑梗死的治疗效果。方法将60例急性进展性脑梗死患者随机分为两组,均给予常规对症治疗。治疗组给予奥扎格雷钠80mg,2次/d,治疗14d,联合应用巴曲酶10U、5U、5U于入院第一天、第三天、第五天静点;对照组给予奥扎格雷钠80mg,2次/d,静滴14d。按照脑卒中患者临床神经功能缺损评分标准进行治疗前、治疗后2周评分。结果 (1)治疗组治疗2周后神经功能缺损评分较治疗前减低,差异有统计学意义(P<0.05);(2)对照组治疗2周后神经功能缺损评分较治疗前减低,差异有统计学意义(P<0.05);(3)两组间治疗后神经功能缺损评分比较,差异有统计学意义(P<0.05)。结论奥扎格雷钠与巴曲酶联合治疗进展性脑梗死疗效优于单用奥扎格雷钠。Objective To evaluate the efficacy of sodium ozagrel combined with batroxobin in the treatment of progressive cerebral infarction. Methods Sixty patients with progressive cerebral infarction were divided into two groups. The two groups were both given casual treatment. The patients in treatment group were given sodium ozagrel 80 mg twice daily for 14 days, combined with batroxobin 10u,5u,5u for the1st day,the 3rd day and the 5th day drip .The patients in control group were given sodium ozagrel 80mg twice daily for 14 days. The two groups were evaluated with cerebral apoplexy clinical neurologic impairment criteria before treatment, 2 weeks after treatment. Results （1） Treatment group’ scores of neurologic impairment was lower after treatment 2 weeks, there was significantly statistical difference（P0.05）.（2） Control group’ scores of neurologic impairment was lower after treatment 2 weeks,there was significantly statistical difference（P0.05）. （3） Treatment group’ scores of neurologic impairment was significantly difference compared with control group’ after treatment, there was significantly statistical difference（P0.05）. Conclusion Cotherapy with sodium ozagrel and batroxobin demonstrates a significant curative effect for progressive cerebral infarction.

关 键 词：巴曲霉 奥扎格雷钠 进展性脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]