麻夷鼻炎喷雾剂挥发性成分的GC-MS分析  

Volatile Components Analysis in Mayi Rhinitis Spray by GC-MS

作　　者：李颖春[1] 郭念欣[1] 姬生国[1] 

机构地区：[1]广东药学院中药学院,广州510006

出　　处：《中国实验方剂学杂志》2010年第15期53-55,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广东省科技计划项目(2009B030801044)

摘　　要：目的:对麻夷鼻炎喷雾剂中挥发性成分进行研究,为该制剂质量标准的制订提供依据。方法:利用GC-MS对挥发性成分进行分离,对分离的各个成分进行结构检索,应用色谱峰面积归一化法测定各成分相对百分含量。结果:共分离出34个成分,鉴定出27个成分,占挥发性成分总量的95.5%。结论:挥发性成分中主要成分为桉油精(19.85%)、龙脑(16.32%)、樟脑(12.54%)、异龙脑(8.4%)、甲基丁香酚(6.08%)、香桧烯(4.19%)。Objective：To investigate the volatile constituents in Mayi Rhinitis Spray and provide some useful information for the quality.Method： The volatile components of Mayi Rhinitis Spray were separated by GC-MS and identified by comparing the structural information given by the MS database.Area normalization method was used to calculate the relative content of each compound of the volatile components.Result： Thirty four compounds were separated,27 compounds were identified,accounting to 95.5% of the total essential components.Conclusion： The principle constituents of the volatile components were eucalyptol（19.85%）,borneol（16.32%）,camphor（12.54%）,isoborneol（8.4%）,methyl eugenol（6.08%）,sabenene（4.19%）.

关 键 词：麻夷鼻炎喷雾剂 挥发性成分 气相色谱-质谱联用技术 

分 类 号：R284.1[医药卫生—中药学]