1型糖尿病患儿血清维生素A浓度变化  

Change of serum concentration of vitamin A in children with type 1 diabetes mellitus

作　　者：陈永兴[1] 卫海燕[1] 王凌飞[1] 刘晓景[1] 李春枝[1] 张英娴[1] 

机构地区：[1]郑州市儿童医院内分泌科,河南郑州450052

出　　处：《临床和实验医学杂志》2010年第21期1609-1609,1611,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨维生素A与儿童1型糖尿病(T1DM)发病机制的关系。方法选取32例T1DM患儿为实验组,28例健康儿童为对照组。微量荧光法检测两组患者血清维生素A水平。结果 T1DM组的血清维生素A水平明显低于对照组,差异有显著性(P<0.01)。结论 1型糖尿病患儿存在维生素A缺乏情况,维生素A缺乏有可能通过对免疫调节的影响而导致T1DM。Objective To explore the relation of vitamin A and the pathogenesis of type 1 diabetes mellitus（T1DM）in children.Methods Totally 32 children with T1DM were taken as experimental group,and 28 healthy children as normal control group.The serum concentration of vitamin A was determined by micro-flourescence method.Results The level of vitamin A in T1DM group was lower than that in control group,and the difference was statistically significant（P0.01）.Conclusion A lack of vitamin A in children with T1DM.Deficiency of vitamin A may result in T1DM through influencing immunoregulation.

关 键 词：儿童 1型糖尿病 维生素A 

分 类 号：R725.8[医药卫生—儿科]