Ⅰ型和Ⅱ型精神分裂症的遗传效应比较  

Comparison of genetics between type Ⅰ and type Ⅱ schizophrenia

作　　者：杨之江[1] 许慧[1] 宋因 

机构地区：[1]江苏苏州市广济医院

出　　处：《临床精神医学杂志》1999年第2期89-90,共2页Journal of Clinical Psychiatry

摘　　要：目的：了解Ⅰ型和Ⅱ型精神分裂症间是否存在遗传效应的差异。方法：调查了精神分裂症Ⅰ型（１８６例）和Ⅱ型（９９例）患者亲属中精神疾病的患病情况。结果：Ⅱ型组有精神疾病家族史多，一级亲属中精神分裂症的发病风险率高，一级亲属的遗传率高，与Ⅰ型组比较，差异均有显著性。结论：Ⅰ型和Ⅱ型精神分裂症间存在着遗传效应差异。Objective:To study the difference in genetics between type Ⅰ and type Ⅱ schizophrenia. Method:Family history of mental illness was studied in 186 patients with type Ⅰ and 99 patients with type Ⅱ schizophrenia. Results:The type Ⅱ group had stronger family history of mental illness.There was also more schizophrenic illness and stronger hereditary load in the first degree relatives. Conclusion:The difference in genetics of type Ⅰ and type Ⅱ schizophrenia suggests the distinct disease nature of the two categories.

关 键 词：精神分裂症.Ⅰ型与Ⅱ型 遗传学 

分 类 号：R749.302[医药卫生—神经病学与精神病学]