早发型和晚发型情感性精神障碍父母育龄及胎次效应比较研究  

A comparetive study of early onset and late onset affective disorders by parental age at delivery and birth order

作　　者：祁曙光[1] 马震祥[1] 刘裴 张震 

机构地区：[1]江苏省镇江市第四人民医院,212001

出　　处：《健康心理学杂志》1999年第2期125-126,共2页Health Psychology Journal

摘　　要：为了解早发型与晚发型情感性精神障碍之间父母育龄及胎次效应有否差异，用Haldame和Smith方法进行了比较研究．结呆表明，晚发型无父母育龄及胎次效应，早发型有父母育龄及胎次效应。这种效应为父母年龄越大、胎次越高，易患情感性精神障碍。提示早发型与晚发型情感精神障碍之间具有遗传异质性。To compare patients with early onset and late onset affective disorders accouding to their parectal age at delivery and birth order. Method Using the Haldame and Smith procedures to study the effects of parectal age and birth order. 113patients with early onst affective disorders were cornpared with 67patients with late onset affective disorders. Results Parental age and birth order were significantly related to late onset, not early onset,affective disorders. The older the parectal age at delivery and the later the birth order,the more likely were patients to develop early onset affective disorders. Conclusion the results suggest that there is a genetic heterogenity in early onset and late onset affective disorders

关 键 词：情感性精神障碍 父母育龄 胎次 遗传异质性 

分 类 号：R749.402[医药卫生—神经病学与精神病学]