超声测量胎儿颈项皮肤厚度的方法及应用价值的深入研究  

Study on the ultrasonography in measurement fetal nuchal fold thickness and application

作　　者：宋雪妮[1] 马喆[1] 展新风[1] 程琳[1] 宋瑶[1] 刘芳[1] 刘昕[1] 刘韶平[1] 

机构地区：[1]山东大学齐鲁医院超声科,济南250012

出　　处：《现代妇产科进展》2010年第11期835-839,共5页Progress in Obstetrics and Gynecology

基　　金：山东省计划生育委员会科学技术发展基金资助(No:012130134-1)

摘　　要：目的:深入研究超声测定胎儿颈项皮肤厚度(NFT)的方法及其临床应用价值。方法:(1)研究4种成像角度及不同超声频率对NFT测值的影响;(2)建立正常胎儿NFT参考值;(3)研究NFT增厚的临床价值。结果:(1)胎头自然俯屈(成像角度145°～155°)或胎头稍仰伸(成像角度135°～145°)NFT差异无统计学意义(P>0.05);(2)15～38周两种频率测量孕周相同胎儿NFT差异有统计学意义(P<0.05);(3)NFT增厚的胎儿中,结局不良者占60.9%。结论:在胎儿颈项正中矢状切面,胎头自然俯屈或胎头稍仰伸两个角度均可作为测量NFT值的标准切面;应用高频超声测量更精确;中期妊娠测定NFT能明显提高异常胎儿检出率,适用于广大基层医院。Objective：To study the method for ultrasonic measurement the fetal nuchal fold thickness（NFT） and its value of clinical application.Methods：（1）The influence of four imaging angles and ultrasonic frequency for NFT were compared.（2）The reference standard of normal NFT was established.（3）Clinical value of thickened NFT was studied.Results：（1）When imaging angle was between 135°～155°,there was no significant difference（P0.05）.（2） For NFT of 15～38 week normal fetus,there was significant difference between 5-2MHz and 12-5MHz measurement（P0.05）.（3）In thickened NFT,bad outcome was 60.9%.Conclusions：In median sagittal section of fetal occipital and two angles with normal flexion or slight extension of fetal head can be the standard plane to measure the NFT.Fetal NFT with high frequency ultrasonography can be accurate.Measurement the NFT in second trimester can obviously enhance the detection rate of chromosomal abnormalities in prenatal diagnosis.

关 键 词：颈项皮肤厚度 成像角度 超声检查 产前诊断 染色体异常 

分 类 号：R714.5[医药卫生—妇产科学]