生物法生产3-羟基丁酮的研究概况  

Present Research Situation of Acetoin Production by Biological Method

作　　者：徐慧[1] 贾士儒[1] 刘建军[2] 

机构地区：[1]天津科技大学天津市工业微生物重点实验室,博士研究生天津300457 [2]山东省食品发酵工程重点实验室,山东济南250013

出　　处：《食品与发酵工业》2010年第11期137-144,共8页Food and Fermentation Industries

摘　　要：3-羟基丁酮是一种重要的风味物质和平台化合物,在食品、化工、医药等行业具有广泛的用途,目前主要以化学合成方法生产。3-羟基丁酮是许多微生物糖代谢的中间产物,以淀粉质原料,生物法生产3-羟基丁酮技术的研究已引起人们的广泛关注,本文综述了生物法生产3-羟基丁酮的研究概况,主要包括3-羟基丁酮生产菌株、代谢机理及相关酶类、代谢调节机制及高效积累策略等。Acetoin （3-hydroxy-2-butanone） is an important flavor compound and platform chemical. It can be widely used in the industry of food, chemical and medicine. At present, the production methods of acetoin are mainly based on chemical synthetic menthods. Acetoin is an important physiological metabolite excreted by many microorganisms, In recent years, the demand of aeetoin has been growing, so the production of acetoin by biological method has attracted people＇s attention. This paper described the present research situation of acetoin production by biological method, which mainly involves aeetoin producing strains, metabolic mechanism, related enzymes and accumulation strategies.

关 键 词：3-羟基丁酮 菌株 发酵 生产 

分 类 号：TQ224.2[化学工程—有机化工]