rhBMP-2/HA/Co复合材料异位诱导成骨中钙含量的检测  

Determining content of calcium in ectopia osteogenesis of rhBMP-2/HA/Co compounds

作　　者：蒋月桂[1] 宋健玲[2] 王宝彦[2] 苟建重[2] 孙斌[3] 孙沫逸[4] 

机构地区：[1]西安交通大学口腔医院牙体牙髓病科,西安710004 [2]西安交通大学口腔医院牙周科,西安710004 [3]西安交通大学口腔医院口腔病理科,西安710004 [4]第四军医大学口腔医学院口腔颌面外科,西安710032

出　　处：《口腔医学》2010年第11期652-654,共3页Stomatology

基　　金：陕西省科技攻关计划资助项目[2002K10-G2(11)];陕西省科技攻关计划项目[2006K10-G3(5)];西安交通大学口腔学院青年科研基金项目(2002YG-6)

摘　　要：目的确定rhBMP-2/HA/Co的生物活性。方法用原子吸收分光光度法测定rhBMP-2/HA/Co复合材料异位诱导成骨区样本单位湿重的钙含量,并与HA/Co组对照。结果实验组样本的单位湿重钙含量的平均值高于对照组。结论 rhBMP-2/HA/Co复合材料具有良好的生物活性。Objective Determining the biological activity of rhBMP-2/HA/Co in order to use it in pulp capping and apexification.Methods Atomic absorption spectrophotometric method was used to evaluate the content of calcium of every sample-unit-wet-weight in ectopia osteogenesis of rhBMP-2/HA/Co and HA/Co.Results The content of calcium in all samples of the unit-wet-weight of rhBMP2/HA/Co group were apparently higher than that the of HA/Co group.Conclusions rhBMP-2 /HA/Co has fine biological activity.

关 键 词：RHBMP-2 Ⅰ型胶原 羟基磷灰石 生物活性 小鼠 钙 

分 类 号：R783.1[医药卫生—口腔医学]