Advances of Bioinformatics Tools Applied in Virus Epitopes Prediction  

作　　者：Simon Rayner 

机构地区：[1]State Key Laboratory of Virology,Wuhan Institute of Virology,Chinese Academy of Sciences

出　　处：《Virologica Sinica》2011年第1期1-7,共7页中国病毒学（英文版）

基　　金：The National Natural Science Foundations of China (30870131);the National Key Projects in the Infectious Fields (2008ZX10002-011, 2008ZX10004-004)

摘　　要：In recent years,the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein,a general overview of different tools currently available,including T cell and B cell epitopes prediction tools,is presented. And the principles of different prediction algorithms are reviewed briefly. Finally,several examples are present to illustrate the application of the prediction tools.In recent years,the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein,a general overview of different tools currently available,including T cell and B cell epitopes prediction tools,is presented. And the principles of different prediction algorithms are reviewed briefly. Finally,several examples are present to illustrate the application of the prediction tools.

关 键 词：EPITOPE BIOINFORMATICS Epitope prediction algorithms 

分 类 号：Q939.4[生物学—微生物学]