冠脉中导引丝与血管骨架空间相对位置的计算  

Calculation of spatial relative position between catheter and vessel centerline in coronary artery

作　　者：王岭[1,2] 陈晓冬[1] 郁道银[1] 

机构地区：[1]天津大学精密仪器与光电子工程学院光电信息技术科学教育部重点实验室,天津300072 [2]长春理工大学光电工程学院,吉林长春130022

出　　处：《光学精密工程》2010年第12期2702-2709,共8页Optics and Precision Engineering

基　　金：国家自然科学基金资助项目(No.30500129);高等学校博士学科点专项科研基金资助项目(No.20030056018)

摘　　要：研究了冠状动脉感兴趣血管段造影图像和血管内超声图像融合的关键技术:导引丝与血管骨架的空间相对位置的计算。首先,通过构造6对匹配点和目标能量函数对几何变换矩阵进行了优化。然后,根据最佳垂平面法求取匹配点间的函数关系,并提出了血管骨架相对于导引丝的空间长度和角度的测量方法和误差分析方法。最后,针对单面冠脉造影图像进行了相对位置的计算。实验结果表明,导引丝与血管骨架重建的平均误差和标准偏差分别降为2.284 3 mm和2.483 1 mm,导引丝与血管骨架相对长度和角度的平均误差分别降为0.498 0 mm和6.029 9°,标准偏差降为0.574 7mm和7.861 9°,基本可以满足图像融合的精度要求。The calculation of spatial relative position between the catheter and the vessel eenterline was investigated,which is a key in the fusion of the single-plane coronary angiograms and the intravascular ultrasound images for segments of coronary arteries. Firstly, the parameters of geometric transformation matrix were optimized by constructing six pairs of matched points and energy functions. Then, the function relationship among the matched points was figured out based on the method of optimal vertical plane, and the measurement method and error analysis method of the lengths and angles for the spatial relative position between the catheter and the vessel centerline were given. Finally,the relative positions were calculated through the single-plane coronary angiograms. The experimental resuits indicate that the average error and the standard deviation of reconstruction have reduced to 2. 284 3 mm and 2. 483 1 mm, the average errors of the length and angle between the catheter and the vessel centerline to 0. 498 0 mm and 6. 029 9°,and the standard deviation to 0. 574 7 mm and 7. 861 9°, respectively. It concludes that the calculation of spatial relative position can improve the accuracy of image fusion and can provide an assistance for doctors in the clinical diagnosis of coronary disease and the interventional treatment.

关 键 词：单面冠脉造影 图像融合 三维重建 相对位置 匹配点对 

分 类 号：R814.43[医药卫生—影像医学与核医学] TP391.4[医药卫生—放射医学]