先天性无虹膜患者中央角膜厚度异常分析  

Analysis of the Abnormality of Central Corneal Thickness of Patients with Congenital Aniridia

作　　者：侯志强[1] 许永根[1] 王薇[1] 

机构地区：[1]北京大学第三医院眼科,北京100191

出　　处：《中国医科大学学报》2011年第2期144-145,152,共3页Journal of China Medical University

基　　金：北京市科学技术委员会资助项目(D206009000091)

摘　　要：目的测量先天性无虹膜患者与正常人的中央角膜厚度,分析差异存在可能的原因。方法选取2008-2009年我院7名确诊为先天性无虹膜患者(14只眼),通过角膜内皮镜观察角膜内皮细胞的形态和密度,通过超声角膜测厚仪测量中央角膜的厚度,50只正常眼做对照。结果患者的平均中央角膜厚度为(645±32.8)μm,正常人为(552±35.6)μm,无虹膜患者的平均中央角膜厚度明显高于正常人,差异有统计学意义(P<0.01);角膜内皮镜检查显示无虹膜患者角膜内皮细胞均正常。结论先天性无虹膜患者的中央角膜厚度明显增加,中央角膜厚度的增加与角膜内皮细胞无关;对于无虹膜患者进行眼压测量,结果会过高估计眼压。Objective To measure and analyze the central corneal thickness（CCT） of the patients with congenital aniridia.Methods Fourteen eyes of 7 patients confirmed diagnosis of congenital anirida were examined by specular microscope to observe the modality and density of corneal endothelial cells.CCT of the patients and 50 eyes of normal subjects were obtained by means of corneal pachymetry.Results The average CCT of patients with aniridia and normal subjects was 645±32.8 μm and 552±35.6 μm respectively.Specular microscope showed normal corneal endothelial cells in patients with aniridia.Conclusion The CCT of the patients with congenital aniridia thickens clearly.Corneal endothelial cells are not responsible for it.The measuring result of intraocular pressure of the patients with aniridia will overestimate their intraocular pressure.

关 键 词：先天性无虹膜 中央角膜厚度 青光眼 

分 类 号：R771[医药卫生—眼科]