1-(5′-溴阿魏酰基)-4-(2′-氯)苄基哌嗪盐酸盐的合成及表征  

Synthesis and characterization of 1-(5′-bromo feruloyl)-4-(2′-chloro)-benzyl piperazine hydrochloride

作　　者：林爱斌[1,2] 张鲁勉[2] 何小英[2] 郑锦鸿[2] 

机构地区：[1]浙江医药高等专科学校药学系,浙江宁波315100 [2]汕头大学医学院化学教研室,广东汕头515041

出　　处：《化学试剂》2011年第2期114-116,共3页Chemical Reagents

基　　金：广东省科技厅科技项目(2004B30101015)

摘　　要：以5′-溴阿魏酸为原料,通过酚羟基的乙酰化保护、羧酸羟基氯代、酰化、脱乙酰基、成盐,制备出的标题化合物为新化合物,未见文献报道,其结构经IR、1HNMR、MS及元素分析确证。The phenolic group of 5′-bromo ferulic acid was protected via acetylation.Then the target compound was prepared via exchange of oxalyl chloride with acid,followed by acylation,deprotection of acetyl,and salification.The novel product obtained thereby had not been reported before.Its structure was confirmed by IR,1HNMR,MS and elemental analysis.

关 键 词：阿魏酸 哌嗪 1-(5′-溴阿魏酰基)-4-(2′-氯)苄基哌嗪盐酸盐 

分 类 号：O626.5[理学—有机化学]