辐照对透明质酸抗氧化性及结构特性的影响  

EFFECT OF IRRADIATION ON ANTIOXIDANT PROPERTIES AND STRUCTURAL CHARACTERISTICS OF HYALURONIC ACID

作　　者：邹朝晖[1,2] 王强[1] 王志东[1] 邓钢桥[2] 李淑荣[1] 高美须[1] 陈永浩[1] 范蓓[1] 李庆鹏[1] 赵宏伟[1] 

机构地区：[1]中国农业科学院农产品加工研究所/农业部农产品加工与质量控制重点开放实验室,北京100193 [2]湖南农业科学院原子能农业应用研究所,湖南长沙410125

出　　处：《核农学报》2011年第1期83-87,共5页Journal of Nuclear Agricultural Sciences

基　　金：中国农业科学院院长基金

摘　　要：用0、1、3、5、8、10、20和40kGy剂量的60Coγ射线对透明质酸溶液进行辐照,研究了辐照对透明质酸分子量、黏度特性及抗氧化性的影响。结果表明:辐照后透明质酸的分子量和黏度特性随剂量的增加而降低;透明质酸对羟自由基(OH.)和超氧阴离子自由基(O2.)的清除率随剂量的增大逐渐减弱,对DPPH.自由基清除作用和还原力逐渐增强;辐照后透明质酸外观品质没有明显的变化,流动性增强;辐照对透明质酸的红外光谱结构没有明显的改变。Effect of 60↑Co γ-rays irradiation on molecular weight,viscosity and antioxidant of hyaluronic acid（HA） were studied in this research.The results showed that molecular weight and viscosity of irradiated HA decreased,the scavenging ability of hydroxyl radicals（OH·） and superoxide radicals（O2·） weakened gradually with the increasing of irradiation dose.However,the DPPH.scavenging ability and reducing power increased with the increasing of irradiation dose.The quality and appearance of HA did not change significantly after irradiation,but the rheology enhanced.The infrared spectra structure of HA did not show significant change after irradiation.

关 键 词：透明质酸 辐照 抗氧化 自由基 

分 类 号：O636.1[理学—高分子化学] Q691.2[理学—化学]