改性β-环糊精微球的制备与表征  

Preparation and Characterization of Modified β-Cyclodextrin Microspheres

作　　者：朱春山[1] 张强[1] 宋佳[1] 

机构地区：[1]河南工业大学化学化工学院,河南郑州450001

出　　处：《高分子材料科学与工程》2011年第3期150-153,共4页Polymer Materials Science & Engineering

基　　金：河南工业大学校科研基金项目(07XJC006)资助

摘　　要：采用反相乳液聚合法制备β-环糊精(β-CD)微球,再用顺丁烯二酸酐(MAH)改性制得丁烯二酸单酯化β-CD微球,探讨了不同工艺参数对改性β-CD微球粒径、分散性的影响。结果表明,在60℃的温度和200r/min～300r/min的电动搅拌,环氧氯丙烷(EPI)和β-CD的质量比为15∶1,复合乳化剂司盘-80和吐温-20的质量比为3∶1的条件下制备的改性β-CD微球粒径和分散性较好,红外光谱图也显示改性β-CD微球上确已引入羧基基团和C=C双键。The β-cyclodextrin（β-CD） microspheres were prepared by inverse emulsion polymerization and modified to achieve the single-esterification maleic acid β-CD microspheres（MAH-β-CD-EPI） with the maleic anhydride（MAH）.The effects of different technique parameters on the particle size and monodispersity of the modified β-CD microspheres were discussed.The results show that the optimum synthesis conditions are 60 ℃of reaction temperature,200 r/min～300 r/min of the motor stirring,the mass ratios of EPI∶β-CD =15∶1 and SP-80∶TW-20=3∶1.The modified β-CD polymer microspheres have the better particle size and monodispersity through bio-microscope,and the microspheres have the carboxyl group and C=C double bond via IR spectrum.

关 键 词：Β-环糊精 微球 改性 

分 类 号：TQ321.2[化学工程—合成树脂塑料工业]