抗癫痫药物与抑郁、焦虑对癫痫患者生活质量的影响研究  

Studying the influence of anti-epilepsy drugs,emotion of depression and anxiety on life quality of patients with epilepsy

作　　者：孙玉凤[1] 李林贵[1] 张文胜 郎颖[1] 刘鸿宇[1] 孙玮[1] 李颖[1] 

机构地区：[1]宁夏医科大学管理学院,宁夏银川750004 [2]宁夏回族自治区卫生厅,宁夏银川750001

出　　处：《中国卫生事业管理》2011年第4期307-309,共3页Chinese Health Service Management

基　　金："十一五"国家科技支撑计划-农村卫生适宜技术及产品研究与应用(强直性脊柱炎等疾病防治技术研究)(项目编号:2007BAI07A00)

摘　　要：目的:探讨采用不同药物治疗癫痫患者在抑郁、焦虑及生活质量方面的差异,并做相关性研究。方法:应用抑郁障碍量表(HAMD)、焦虑自评量表(SAS)及癫痫患者生活质量-31量表(QOLIE-31)对82例采用苯巴比妥药物治疗癫痫的患者及82例采用混合药物治疗癫痫的患者进行评定,对照分析采用不同药物患者的心理情绪及生活质量,并做相关性分析。结果:采用苯巴比妥与采用一般药物治疗癫痫患者在抑郁、焦虑及生活质量总评方面均无统计学差异,而生活质量评价中除"情绪"项外均与HAMD、SAS评分成负相关。Objective To explore the influence of anti-epilepsy drugs on life quality,emotion of depression and anxiety of patients with epilepsy.Methods 82 cases of patients with epilepsy treated with Phenobarbital and 82 cases treated with mixed drugs were respectively evaluated with scales of HAMD,SAS and QOLIE-31,and their emotion and quality of life were comparatively analyzed.Results There had no significant difference in emotion of depression and anxiety and life quality between patients treated with Phenobarbital and patients with mixed drugs.Life quality evaluation,except the item of emotion,was significantly negatively correlated with scores of HAMD and SAS.

关 键 词：癫痫 苯巴比妥 生活质量 

分 类 号：R742.1[医药卫生—神经病学与精神病学]