Effect of the Extract from Hypericum perforatum on Highly Pathogenic Avian Influenza Virus(HPAIV)  

作　　者：LIANG Jian-pingt SHANG Ruo-feng WANG Xue-hong GUO Zhi-ting GUO Wen-zhu HAO Bao-cheng WANG Shu-yang TAO Lei LI Xue-hu LU Xi-hong 

机构地区：[1]Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 [2]Key Laboratory of New Animal Medicine Project, Chinese Academy of Agricultural Sciences, Lanzhou Institute of Animal Husbandry ＆ Veterinary Pharmaceutics Science, Chinese Academy ofAgricultural Sciences, Lanzhou 730050

出　　处：《Agricultural Science & Technology》2010年第11期107-110,共4页农业科学与技术（英文版）

基　　金：Supported by Hundred Talent Program of Chinese Academy of Sciences(O861010ZY0);Key Technologies R&D Program(2004BA519A26)

摘　　要：[Objective] The aim was to study the effects of the extract from Hypericum perforatum on highly pathogenic Avian Influenza Virus(HPAIV)in vivo.[Method] Chickens infected with H5N1 virus were treated with the extract from H.perforatum for 4 d.The virus was then detected by hemoagglutination(HA)test and reverse transcription polymerase chain reaction(RT-PCR).[Result] No H5N1 virus could be detected at the 7th d when the chickens were treated with 0.2 or 0.1 g/(kg·d)of the extract from H.perforatum.However,the virus could be detected in other chickens without the extract from HPE treatment.[Conclusion] The extract from H.perforatum might be a potential drug candidate to control infection of H5N1 subtype AIV in chickens.[Objective] The aim was to study the effects of the extract from Hypericum perforatum on highly pathogenic Avian Influenza Virus(HPAIV)in vivo.[Method] Chickens infected with H5N1 virus were treated with the extract from H.perforatum for 4 d.The virus was then detected by hemoagglutination(HA)test and reverse transcription polymerase chain reaction(RT-PCR).[Result] No H5N1 virus could be detected at the 7th d when the chickens were treated with 0.2 or 0.1 g/(kg·d)of the extract from H.perforatum.However,the virus could be detected in other chickens without the extract from HPE treatment.[Conclusion] The extract from H.perforatum might be a potential drug candidate to control infection of H5N1 subtype AIV in chickens.

关 键 词：HYPERICUM perforatum(HPE)preparation H5N1 SUBTYPE AIV HA RT-PCR 

分 类 号：S[农业科学]