鞍区肿瘤的脑电图特征(附224例分析)  

The EEG of sella turcica region tumor: an analysis of 224 cases

作　　者：吴维华[1] 吴萍嘉[1] 

机构地区：[1]第二军医大学长征医院神经内科,上海200003

出　　处：《第二军医大学学报》1999年第8期568-570,共3页Academic Journal of Second Military Medical University

摘　　要：目的：探索鞍区肿瘤的脑电图（ Ｅ Ｅ Ｇ）特征。方法：２２４ 例经手术和（或）病理、 Ｃ Ｔ、 Ｍ Ｒ Ｉ证实的鞍区肿瘤分成３ 组：（１）垂体腺瘤组１５３ 例；（２）颅咽管瘤组４６ 例；（３）鞍区其他肿瘤组２５ 例。所有患者均按常规方法在手术前２～３０ ｄ 内记录 Ｅ Ｅ Ｇ。结果：过半数的患者（５７．６％ ）呈现正常或轻度异常 Ｅ Ｅ Ｇ，其余患者（４２．４％ ）表现 Ｅ Ｅ Ｇ 异常，其中弥漫性异常２９．０％ ，阵发性异常８．５％ ，局灶性异常４．９％ 。此外，有２４ 例（１０．７％ ）出现间歇性节律性δ活动（ Ｉ Ｒ Ｄ Ａ），７７ 例（３４．４％ ）有生理波抑制现象。 Ｉ Ｒ Ｄ Ａ及生理波抑制在颅咽管瘤组中的出现率明显高于其他两组。直径＞ ２０ ｍ ｍ 的鞍区肿瘤 Ｅ Ｅ Ｇ 异常率高。结论：鞍区肿瘤的 Ｅ Ｅ Ｇ以无特征性改变占主导地位，其 Ｅ Ｅ Ｇ 异常的主要表现形式是弥漫性及阵发性异常，少有局灶性异常出现。肿瘤体积与异常程度呈正相关。 Ｅ Ｅ Ｇ 对鞍区肿瘤的定性诊断有一定帮助。Objective: To investigate the characteristics of the electron encephalogram (EEG) of the sella turcica region tumor (STRT). Methods: Two hundred and 24 patients with STRT, confirmed by surgery, pathology, CT or MRI, were divided into 3 groups: (1) Pituitary adenoma (153 cases). (2) Craniopharyngioma(46 cases). (3) Other tumors in sella turcica region (25 cases). EEG were recorded with conventional method 2~30 days before operation. Results: Over half of the patients (56.7%) had normal or mild abormal EEGs. The rest of the patients had diffuse abnormal EEGs (29 0%), paroxysmal abnormal EEGs (8.5%) or local abnormal EEGs(4.9%). 24 cases displayed intermittent rhythmic delta activities (IRDA, 10.7%). Seventy seven cases showed an inhibition of physiological waves. IRDA and inhibition of physiological waves frequently appeared in the EEGs of the craniopharyngioma group. The rate of the abnormality of EEG in the patients with large tumor (D>2 cm) was higher than that of the patients with small tumor (D<2 cm). Conclusion: Non specific changes in EEG are the predominant manifestations in STRT. The main characteristics of the abnormal EEGs in STRT are diffuse or paroxysmal abnormality. Only a few cases have local abnormal EEGs. The extent of abnormality in EEGs correlates to the size of tumor. EEG is helpful in qualitative diagnosis of STRT.

关 键 词：鞍区肿瘤 脑电图 EEG 

分 类 号：R739.410.4[医药卫生—肿瘤] R741.044[医药卫生—临床医学]