鲍鱼性腺多糖的体内抗氧化活性  

Antioxidant activity of polysaccharide extracted from abalone gonad

作　　者：刘娜[1] 朱蓓薇[1] 孙黎明[1] 刘俊荣[2] 

机构地区：[1]大连工业大学食品学院,辽宁大连116034 [2]大连海洋大学食品工程学院,辽宁大连116023

出　　处：《大连工业大学学报》2011年第3期177-179,共3页Journal of Dalian Polytechnic University

基　　金：国家高技术研究发展计划(863计划)项目(2007AA091804);国家"十一五"科技支撑计划项目(2008BAD94B07);辽宁省重点实验室项目(2008403003);辽宁省教育厅创新团队项目(2009T033;2008T007)

摘　　要：采用酶水解结合乙醇醇沉的方法从皱纹盘鲍性腺中提取多糖(CAGP),并研究其体内抗氧化活性。研究发现,对于正常小鼠,200 mg/kg的CAGP可有效提高其肝组织中CAT活力及T-AOC能力(P<0.01),降低血液与肝脏MDA浓度(P<0.01);CAGP还可显著降低脑组织MAO活力(P<0.01)。对于四氧嘧啶致氧化损伤的高脂血症大鼠,200 mg/kg的CAGP能有效降低大鼠血清MDA浓度(P<0.01),提高血清SOD活力(P<0.01),同时肝脏T-AOC也有显著提高(P<0.01)。鲍鱼性腺多糖能够显著提高正常小鼠及氧化损伤大鼠机体的抗氧化能力,可用于抗氧化功能食品的研究开发。Crude abalone gonad polysaccharide（CAGP） was extracted from gonad of abalone Haliotis Discus Hannai Ino by protease hydrolysis and ethanol precipitation.For normal mice,CAGP can improve CAT activity and T-AOC（P0.01） at dosage of 200 mg/kg,and significantly reduce the MDA content in blood and liver and MAO activity in brain tissue（P0.01）.For oxidatively damaged rats,CAGP can protect damage from alloxan.The SOD activity and T-AOC were significantly increased in the rat administered with 200 mg/kg of CAGP（P0.01）.MDA content in blood was also significantly reduced（P0.01）.Results suggested that CAGP could enhance the antioxidant activity in both normal mice and oxidatively damaged rats,which could be applied in antioxidant functional food development.

关 键 词：鲍鱼 鲍鱼性腺多糖 抗氧化 

分 类 号：TS254.1[轻工技术与工程—水产品加工及贮藏工程] Q53[轻工技术与工程—食品科学与工程]