2010年太原市普通人群血清中多溴联苯醚负荷水平  

Polybrominated diphenyl ethers load in human serum of Taiyuan city in 2010

作　　者：黄飞飞[1] 李敬光[1] 张磊[1] 闻胜[2] 郭斐斐[3] 赵云峰[1] 吴永宁[1] 

机构地区：[1]中国疾病预防控制中心营养与食品安全所,北京100050 [2]湖北省疾病预防控制中心卫生监测检验防护所 [3]山西医科大学公共卫生学院

出　　处：《中华预防医学杂志》2011年第6期502-505,共4页Chinese Journal of Preventive Medicine

基　　金：＂十一五＂国家科技支撑计划（2007BAC27B02）;卫生公益性行业科研专项（200902009）;中国博士后科学基金（20090450459）

摘　　要：目的 研究太原市普通人群血清中多溴联苯醚（PBDEs）负荷水平.方法 2010年在太原市共采集了42份普通人群血清样品,用固相萃取-气相色谱-负化学源-质谱法测定了样品中溴代联苯醚（BDE）-17、BDE-28、BDE-47、BDE-66、BDE-99、BDE-100、BDE-153、BDE-154、BDE-183 和BDE-209,计算PBDEs合计值（∑PBDEs）.结果 在测定的血清样品中,∑PBDEs范围为2.09-66.74 ng/g脂重（lipid weight,1w）,中位数和均值分别为6.32 ng/g 1w和9.84 ng/g 1w.BDE-209为ΣPBDEs主要贡献来源,其含量在未检出至64.99.ng/g 1w范围内,中位数为4.11 ng/g 1w,其贡献率为67.6%;其次为BDE-153,其含量在0.29-4.92 ng/g 1w范围内,中位数为0.62 ng/g 1w,其贡献率为10.1%.结论 2010年太原市普通人群血液中PBDEs负荷水平较低.Objective This study was conducted to characterize polybrominated diphenyl ethers （PBDEs）load in human serum of Taiyuan city in 2010.Methods A total of 42 blood samples were collected in Taiyuan city,2010.Solid-phase extraction（SPE）-gas chromatography-negative chemical ionization-mass spectrometry method was used to measure the concentration of brominated diphenyl ethers （BDE）-17,BDE-28,BDE-47,BDE-66,BDE-99,BDE-100,BDE.153,BDE-154,BDE-183 and BDE-209 and ∑PBDEs was calculated.Results Of the tested serum samples,∑PBDEs ranged from 2.09 to 66.74 ng/gof lipid weight（1w）,the median and mean was 6.32 ng/g 1w and 9.84 ng/g 1w.respectively.BDE-209 was the main source of ∑PBDEs and its concentration ranged from no dectecion to 64.99 ng/g 1w.the median was 4.11 ng/g 1w,accounting for 67.6%of ∑PBDEs.Second source was BDE-153 and its concentration ranged from 0.29 to 4.92 ng/g 1w,the median was 0.62 ng/g 1w accounting for 10.1% of ∑PBDEs.Conclusion The overall load of PBDEs in the serum of local residents was low in 2010.

关 键 词：多溴联苯类 血清 人群监测 多溴联苯醚 

分 类 号：R114[医药卫生—卫生毒理学]