亚硫酸钠还原法合成邻乙基苯肼  

Synthesis of o-Ethylphenylhydrazine with Sodium Sulfite Reduction

作　　者：陈永杰[1] 徐大军[1] 郝晶 王勇[1] 

机构地区：[1]沈阳化工学院,辽宁沈阳110021

出　　处：《沈阳化工学院学报》1999年第4期243-247,共5页Journal of Shenyang Institute of Chemical Technolgy

摘　　要：将邻乙基苯胺与亚硝酸钠反应生成重氮盐，再经亚硫酸氢钠（ 亚硫酸钠） 还原制得邻乙基苯肼．采用盐酸洗涤法和柱层析法对产品进行了提纯．通过薄层色谱、红外光谱、核磁共振波谱及熔点测定等方法确定了产品结构．A synthesis of \%o\%\|ethylphenylhydrazine is described with the features of the reaction of \%o\%\|ethylaniline with sodium nitrite to produce diazo and followed by reduction with sodium bisulfite (or sodium sulfite). The product is purified through hydrochloric acid washing method and column chromatography. The structure of the product is determined by means of TLC, IR and NMR.

关 键 词：邻乙基苯胺 邻乙基苯肼 亚硫酸氢钠 还原法 制药 

分 类 号：TQ246.6[化学工程—有机化工] TQ460.4