诺丽果汁对老龄小鼠抗氧化功能影响的实验研究  

Study on evaluation of antioxidant activity of Noni juice in vivo

作　　者：张建军[1] 王林元[1] 欧丽娜[1] 苗春平[1] 徐媛[1] 刘妍[1] 金磊[1] 钱丽丽[1] 龙锐[1] 

机构地区：[1]北京中医药大学,北京100029

出　　处：《食品工业科技》2011年第7期392-393,406,共3页Science and Technology of Food Industry

摘　　要：目的:探讨诺丽果汁对老龄小鼠抗氧化功能的影响。方法:老龄动物模型法,采用5、10、30mL/kg·bw剂量的诺丽果汁给老龄小鼠灌胃,于末次给药后,分别测定血中丙二醛(MDA)的含量和肝组织中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)的活力。结果:与空白老龄对照组比较,诺丽果汁5、10、30mL/kg·bw剂量组能显著提高肝组织中SOD、GSH-Px活力,降低血中过氧化脂质MDA含量。结论:诺丽果汁具有抗氧化功能。Objective ：To research the anti- oxidative activity of Noni juice in aged mice. Method. Tahitian Noni juice （TNJ）was administrated by gavage[5,10,30mL/（ kg · bw） ] to male mice（ tO-month-old CL ICR） for 30d.The mice were then sacrificed, and the blood and the livers were collected. The concentration of malondialdehyde （MDA） in the blood and the level of superoxide dismutase（SOD） and glutathione peroxidase（GSH-Px） in the liver were then measured by spectrophotometry. Result：TNJ produced a dose-dependent decrease of MDA, at the same time a dose-dependent increase of SOD and GSFI-Px at all three doses.Conclusion：TNJ had antioxidant activity by protecting body against free radical-induced damage.

关 键 词：诺丽果汁 老龄小鼠 抗氧化功能 

分 类 号：TS275.5[轻工技术与工程—农产品加工及贮藏工程]