茶多酚对肥胖大鼠器官指数及腹脂的影响  

Effect of tea polyphenols on organ index and abdominal tat in rats

作　　者：顾有方[1] 吴珍龙[1] 李升和[1] 

机构地区：[1]安徽科技学院,安徽凤阳233100

出　　处：《中国兽医学报》2011年第7期1024-1026,共3页Chinese Journal of Veterinary Science

基　　金：安徽省高等学校学科拔尖人才基金项目(2005043)

摘　　要：将80只21日龄SD大鼠,按体质量相近原则分为普通对照组(Ⅰ组)、模型对照组(Ⅱ组)、试验Ⅲ组、试验Ⅳ组、试验Ⅴ组和试验Ⅵ组,每组10只大鼠,试验期80d;普通对照组饲喂基础日粮,其他各组饲喂高能高脂日粮,40d后,试验Ⅲ、Ⅳ、Ⅴ、Ⅵ组分别灌服10、20、40、80mg/kg.d茶多酚,普通对照组与模型组灌服等体积生理盐水,至80d试验结束后禁食不禁水12h,逐只称重,剖检取腹脂(睾丸周围和后腹部脂肪)、心、肝、脾、肺、肾并称重。结果显示,在制模后,与普通对照组与模型对照组相比,试验Ⅲ、Ⅳ、Ⅴ、Ⅵ组腹脂重量差异极显著(P<0.01);灌服茶多酚试验组的大鼠各器官指数与对照组差异不显著(P>0.05)。结果表明,茶多酚对肥胖大鼠器官指数无影响,对腹脂重量有抑制作用。Eighty SD rats were adaptive fed one week. 60 SD rats were randomly selected and divided into Ⅰ , Ⅱ , Ⅲ, Ⅳ, Ⅴ, Ⅵ groups of 10 each according to the principle of similar weight. Ⅰ , Ⅱ group were the model control group and general control group, Ⅲ , Ⅳ, Ⅴ , Ⅵ group were TP experimental group, total trial period lasted for 80 d. SD rats in Ⅱ group were fed the basic ration,other groups were fed the high-energy feedstuff. After /10 d,SD rats in Ⅲ , Ⅳ, Ⅴ , Ⅵ group were orally dosed 10,20,40,80 mg/kg · d TP, Ⅰ and Ⅱ group were administrated the saline until 1be 80 d. At the experiment end,SD rats were fasting and not prohibited drinks for 12h, weighted, anaesthetized with 10%; chloral hydrate aldehyde（2.0 mL/kg body weight）. Abdominal fat（around the testicle and post abdominal fat）and organ （heart, liver, spleen, lung, kidney） were taken and weighted. After established fatted model of SI） rats, compared with the common control group and model control group,there was significant difference in abdominal fat weight of Ⅲ , Ⅳ, Ⅴ , Ⅵ group（P〈0.01） ,but organs index had no difference（P〉0.05）. There was no effeet of tea polyphenol on organs index,it could inhibit the abdominal fat weight of rat.

关 键 词：茶多酚 SD大鼠 器官指数 腹脂 

分 类 号：S859.7[农业科学—临床兽医学]