用文献综述法估计我国食源性非伤寒沙门氏菌病疾病负担  

Estimation on disease burden of foodborne non-typhoid salmonellosis in China using literature review method

作　　者：毛雪丹[1] 胡俊峰[2] 刘秀梅[1] 

机构地区：[1]中国疾病预防控制中心营养与食品安全所标准与监督技术室,北京100021 [2]中国健康教育中心,北京100011

出　　处：《中华疾病控制杂志》2011年第7期622-625,共4页Chinese Journal of Disease Control & Prevention

摘　　要：目的估计我国食源性非伤寒沙门氏菌病造成的疾病负担,为我国食源性疾病主动监测网络的建立提供依据。方法利用文献综述方法估计我国急性腹泻发病率以及腹泻人群中非伤寒沙门氏菌的比例,利用食源性疾病监测网获得非伤寒沙门氏菌感染患者的腹泻发生比例,利用文献综述获得非伤寒沙门氏菌的食源性比例。综合腹泻发病率及各项乘数获得食源性非伤寒沙门氏菌病的发病率。利用卫生部第三次死因调查报告及文献资料,估计非伤寒沙门氏菌导致的死亡病例。结果 2000-2009年,每年因非伤寒沙门氏菌导致急性腹泻823.5万人次,导致急性胃肠炎病例估计为987.4万人次。利用食源性比例91.5%,估计我国食源性非伤寒沙门氏菌病每年发病约903.5万人次,每年死亡估计792人。结论在我国非伤寒沙门氏菌是重要的食源性致病菌,可能造成较重的疾病负担。我国非伤寒沙门氏菌感染占急性胃肠炎的比例与发达国家类似,病死率低于美国、新西兰,文献综述的方法与国外的科学设计仍有一定差距,应加强我国食源性疾病主动监测网的建立,完善实验室监测网络。Objective To estimate the disease burden of foodborne non-typhoid salmonellosis in China. Methods The occurrence rate of acute diarrhea and the proportion of non-typhoid salmonella were evaluated by literature reviews. The occurence rate of foodborne non-typhoid salmonellosis was calculated by the acute diarrhea morbidity multiplied the factors, including the proportion of non-typhoid salmonella among the diarrhea cases, the diarrhea proportion among the non-typhoid salmonellosis cases from National Foodborne Disease Monitoring Network, foodborne proportion of non-ty- phoid salmonella infection. The death information was obtained from the third report of death investigation in China from MOH. Results During 2000 - 2009, non-typhoid salmonella annually caused 8 235 000 diarrhea cases, from which 9 874 000 gastroenteritis cases were deduced, 9 035 000 cases were infected by food transmission. Annually 792 deaths were estimated. Conclusions Non-typhoid salmonella is still one of the main foodborne pathgens in our country and caus- es heavy burden on China. The proportion of non-typhoid salmonellosis cases among gastroenteritis is similar to developed countries in China, and the fatality rate is lower than developed countries. There＇ s some gap between the method by liter- atures review in China and the well-designed laboratory surveillance. Therefore, the foodborne disease active surveillance including laboratories surveillance should be set up.

关 键 词：沙门菌病 食源性疾病 疾病负担 

分 类 号：R181.1[医药卫生—流行病学] R183[医药卫生—公共卫生与预防医学]