管状胃代食管减轻食管癌术后胃食管反流的临床效果  

Clinical outcomes of easophageal reconstruction with tube-shaped stomach in attenuating gastroeasophageal reflux in patients underwent resection of easophageal carcinoma

作　　者：徐海萍[1] 骆金华[1] 孙杰[1] 徐晓晗[1] 

机构地区：[1]南京医科大学第一附属医院手术室,210029

出　　处：《江苏医药》2011年第14期1691-1693,共3页Jiangsu Medical Journal

摘　　要：目的探讨管状胃代食管术后胃食管反流程度。方法按手术方式将31例食管癌患者分为管状胃(A)组和传统手术(B)组。术后1周,胃肠功能动态pH值监测仪测定24 h的pH值。记录全天的反流次数、长反流(>5 min)次数、最长反流持续时间、pH<4的时间及其占全天的比率。结果与B组比较,A组反流次数少[(10.85±16.85)次vs.(0.22±0.44)次],长反流次数少[(2.00±0.00)次vs.(0.42±0.78)次],最长反流持续时间短[(4.28±6.04)min vs.(0.22±0.66)min],时间pH<4(pH<4的时间)短[(15.00±18.60)min vs.(0.55±0.88)min],时间pH<4分数(pH<4的时间占全天的比率)小[(1.18±1.44)%vs.(0.05±0.13)%],DeMeester评分低(4.90±6.07)分vs.(0.42±0.29)分。Objective To investigate the clinical outcomes of easophageal reconstruction with tube-shaped stomach in attenuating gastroeasophageal reflux in patients underwent resection of easophageal carcinoma.Methods Redical section was performed in 31 patients with easophageal carcinoma and easophageal reconstruction was made with tube-shaped stomach（group A,16 cases） or conventional tecnique（group B,15 cases）.The indicators evaluating gastroeasophageal reflux one week after operation were recorded and monitored with dynamic gastroentestinal function and 24-h pH monitor.Results Compared to group B,the pstients in group A had less times of reflux[（10.85±16.85） times vs.（0.22±0.44） times] and the times of long-lasting（5 min） reflux [（2.00±0.00） times vs.（0.42±0.78） times],shorter lasting of maximum long-lasting reflux[（4.28±6.04） min vs.（0.22±0.66） min],shorter time of pH less than 4[（15.00±18.60） min vs.（0.55±0.88） min] and less ratio of the time of pH less than 4 to 24 hours[（1.18±1.44）% vs.（0.05±0.13）%],and less DeMeester score [（4.90±6.07） points vs.（0.42±0.29）points（P0.05）.Conclusion Gastric tube reconstruction can decrease the incidence of gastroeasophageal reflux in easophageal carcinoma patients.

关 键 词：管状胃 食管重建 胃食管反流 食管癌 

分 类 号：R735[医药卫生—肿瘤]