饮食防治前列腺癌  

Dietary intervention of prostatic cancer(literature review)

作　　者：刘国栋[1] 刘晓[2] 马宝良[3] 

机构地区：[1]兰州大学第二医院泌尿外科研究所,兰州730030 [2]甘肃省泌尿系疾病临床医学中心,兰州730030 [3]甘肃省泌尿系疾病重点实验室,兰州730030

出　　处：《现代泌尿外科杂志》2011年第4期287-289,共3页Journal of Modern Urology

摘　　要：流行病学及病理研究证实,前列腺癌的发生和发展与饮食习惯、生活方式明显相关。文献还证实,低脂肪饮食,尤其来源于鱼油的n-3脂肪酸,及蔬菜、水果和豆类中的多酚类、异黄酮、番茄红素、类胡萝卜素及没食子,通过调节性激素、胰岛素/IGF轴及基因,可降低前列腺癌细胞生长、异种移植癌生长、细胞增殖,并增加凋亡,从而达到抑制前列腺癌生长和发展的作用。对前列腺癌患者,进行低脂肪饮食干预,可提高生活质量,且可使PSA倍增时间延长,增加存活。此法有效、安全、省钱、易行,值得推广。Epidemiological and pathological findings have validated that the genesis and progress of prostatic cancer is closely related to diet and living style. Low-fat diet, especially n-3 lipid acid from fish oil, polyphenols, isoflavone, lycoypene, carotenoid and nutgall from vegetables, fruits and beans, are able to inhibit the growth of prostatic cancer by regulating sexual hormones, insulin/ IFG axis and genes, thus restraining the growth of prostatic cancer cells, xenogenesis cancer ceils and cell proliferation, and increasing apoptosis. Patients with prostatic cancer can improve life quality and survival rate by taking low- fat diet, which is effective, safe, economical and feasible.

关 键 词：饮食干预 低脂肪 多酚 异黄酮 番茄红素 胡萝卜素 胰岛素/IFG轴 基因 

分 类 号：R737.25[医药卫生—肿瘤]