酶法制备甲壳低聚糖研究的进展  

Advance in chitosan oligosaccharides with enzymatic method:a review

作　　者：程仕伟[1] 孙爱友[2] 

机构地区：[1]鲁东大学生命科学学院,烟台264025 [2]华东理工大学生物反应器工程国家重点实验室,上海200237

出　　处：《生物加工过程》2011年第5期65-70,共6页Chinese Journal of Bioprocess Engineering

基　　金：国家自然科学基金资助项目(20706017);鲁东大学校科研基金资助项目(LY20083305)

摘　　要：甲壳低聚糖具有多种重要的生理活性,可作为食品添加剂、生物农药和新型药物,是低聚糖研发的新热点。与壳聚糖相比,由于多糖链缩短使其水溶性好、黏度低且容易吸收。本文对酶法制备甲壳低聚糖的催化剂种类和特性、生物反应器选用及其工艺优化的最新进展进行综述,对酶法生产甲壳低聚糖进行总结并展望未来的研发重点。Chitosan oligosaccharides had shown various functional properties, and were used in many fields including fooding, agriculture and biomedicine. Compared with chitosan, chitosan oligosaccharides were readily soluble in water due to their short chain lengths, low viscosity and easily absorbed in vivo. In this paper, recent advances were discussed about types and characteristics of the used enzymes, bioreactor selection and process optimization in the enzymatic production of chitosan oligosaccharides. Furthermore, it summarized and outlook the future emphasis in the research and development by using enzymatic producing chitosan oligosaccharides.

关 键 词：生物反应器 壳聚糖酶 甲壳低聚糖 酶法 

分 类 号：Q814.9[生物学—生物工程]