脑脊液乳酸联合酶活性测定在脑梗死中的临床应用价值  

The clinical value of cerebrospinal fluid lactic acid and enzyme activity in the treatment of cerebral infarction

作　　者：赵凯[1] 

机构地区：[1]河南省商丘市第一人民医院,476100

出　　处：《中国医学创新》2011年第29期85-86,共2页Medical Innovation of China

摘　　要：目的探讨脑梗死患者的脑脊液乳酸、蛋白含量和酶活性变化的临床意义。方法应用全自动生化分析仪检测87例脑梗死患者和32例无神经系统疾病需外科手术的腰麻患者的脑脊液乳酸(LA)、总蛋白、CRP、LDH、AST活性,并进行统计学分析。结果对照组脑脊液LA、总蛋白、CRP、LDH、AST和酶活性结果明显低于脑梗死组(P<0.01),对照组脑脊液ADA低于脑梗死组,但差异无统计学意义。结论脑脊液乳酸、蛋白含量和酶活性变化对脑梗死的疗效观察以及预后判断有重要的临床意义。Objective To investigate the clinical value of cerebrospinal fluid（CSF）, lactic acid（LA）, protein, and enzyme activity in brain infaretion. Methods 87 cases of brain infarction and 30 cases of control were hrought into study, collected the CSF, then measured the laitic acid（ LA）, total protein （TP）, C -reactive protein （CRP）, and enzyme activity （LDH, ADA, AST） with automatic biochemical analyzer, and analyzed the result with statistic method. Results Compared with enntrol group, the SF - LA, CSP - TP, CSF - CRP, CSF - LDH, CSF - AST level were high obviously in brain infarction group（ P 〈 0.01 ）, but the decreasing of CSF - ADA without significant difference（ P 〉 0. 05 ）. Conclusion The changes of cerebrospinal fluid LA, protein and enzyme activity have an important role in monitoring curative effect and estimating prognosis for brain infarction.

关 键 词：脑脊液 乳酸 蛋白质 脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]