Lanthanides' enhancing absorption of insulin and reduction of blood glucose of rat by pulmonary administration  

作　　者：Yi Cheng Zancong Shen Qiang Zhang Rongchang Li Shuli Wei Kui Wang 

出　　处：《Chinese Science Bulletin》2000年第7期604-608,共5页

摘　　要：To explore the possibility of lanthanides as the enhancer of insulin absorption, the promoting effects of lanthanide ions on the absorption of intrapulmonary delivered insulin and reduction of blood glucose were investigated by means of two approaches, preadministration and coadministration of lanthanide ions with insulin. The results indicate that, compared with the results of those given insulin only, lanthanide ions can effectively enhance the level of insulin and the reduction of glucose level in blood. These effects are dependent on lanthanide species and their concentrations. The mechanism was discussed.To explore the possibility of lanthanides as the enhancer of insulin absorption, the promoting effects of lanthanide ions on the absorption of intrapulmonary delivered insulin and reduction of blood glucose were investigated by means of two approaches, preadministration and coadministration of lanthanide ions with insulin. The results indicate that, compared with the results of those given insulin only, lanthanide ions can effectively enhance the level of insulin and the reduction of glucose level in blood. These effects are dependent on lanthanide species and their concentrations. The mechanism was discussed.

关 键 词：LANTHANIDE INSULIN BLOOD GLUCOSE rat. 

分 类 号：R965[医药卫生—药理学]