食管癌病人血清及癌组织游离氨基酸谱的临床研究  

The clinical evaluation of free amino acid spectrun of serum and cancer tissue in patients with esophageal carcinoma

作　　者：王桂洪[1] 秦文瀚[1] 黎君友[2] 晋桦[2] 

机构地区：[1]北京空军总医院胸外科,100036 [2]解放军三○四医院

出　　处：《中华临床营养杂志》1997年第4期174-176,共3页Chinese Journal of Clinical Nutrition

摘　　要：应用氨基酸自动分析仪，对22例食管癌病人血清，正常食管组织和食管癌组织游离氨基酸含量分析。结果表明：食管癌病人血清有7种氨基酸降低，2种升高；食管癌组织游离氨基酸较正常食管组织显著增多，血清下降显著的几种氨基酸，在癌组织中增加比例明显。提示食管瘤病人血和组织游离氨基酸代谢紊乱。Free amino acid spectrum of blood serum , esophageal tissue and esophageal cancer tissue were analyzed with Automatic Amino Acid Analyzer in 22 patients with esophageal carcinoma . It is concluded that the concentration of 7 serum free amino acids wer depleted and 2 free amino acids were elevated in the esophageal carcinoma patients than that of 22 normal controls, while the concentration of 18free amino acids in esophageal cancer tissue are higher than that of normal esophageal tissue (P< 0.01).The depleted concentration of free amino acids in serum are those of incerased in cancer tissue correspondingly. It is suggested that there are som metabolic derangement of free amino acid spectrum in serum and esophageal cancer tissue in the esophageal carcinoma patients .

关 键 词：食管癌 游离氨基酸 

分 类 号：R735.1[医药卫生—肿瘤]