应用乳杆菌溶液治疗特异性、非特异性阴道炎  

OBSEVATION OF THE THERAPEUTIC EFFCTS OF LACTOBACILLUS ON PATIENT WITH NON-SPECIFIC VAGINITIS AND TRICHOMONAS VAGINITIS

作　　者：李丽秋[1] 马树霞[1] 韩秀坤[1] 卓越[1] 吕密凯[2] 李会明[2] 刘富荣[3] 徐晓梅[3] 王忠英[4] 李瑞昌 

机构地区：[1]佳木斯医学院微生物教研室,佳木斯154002 [2]佳木斯医学院生理教研室,佳木斯154002 [3]佳木斯医学院妇产科,佳木斯154002 [4]佳木斯市妇婴医院,佳木斯154002 [5]佳木斯市永红区医院,佳木斯154003

出　　处：《中国微生态学杂志》1993年第1期43-47,共5页Chinese Journal of Microecology

摘　　要：阴道炎并非一种独立的疾病,而是多种特异性和非特异性炎症的总称。妇女在一生中未曾患过阴道炎者极少,甚至有少数恶者炎症反复发作。阴道内固有菌一般是不致病的,但是阴道手术,局部创伤,分娩、流严、以及应用大量免疫抑制剂或抗生素的情况下,可转化为致病菌,这些致病菌,往往是盆腔感染的最常见病原。乳杆菌是阴道生理性细菌,是良好的生物屏障,我们应用乳杆菌溶液在一年半时间内,对50例非特异性阴道炎、50例滴虫性阴道炎、50例霉菌性阴道炎进行了治疗,并同时进行了菌群分析,结果表明,这三组阴道炎病人的阴道中,乳杆菌的平均浓度明显低于正常值,而肠杆菌、葡萄球菌和类杆菌明显增高,因此,阴道炎是由于菌群失调而引起的。乳杆菌是阴道中正常优势菌,对致病菌有抵抗作用对维持阴道微生态环境,保持健康状态是非常重要的。The preparation of laetobaeillus was used in 30 cases of Non-specific vaginitis and cased of trichomonas vaginitis, and the analyses of culture the vaginal flora were performed on the patients. The results showed that the mean levels of lactobacili was significantly lower in the patients than that in healthy women wheras mean levels of Enterobacteriaseae, Staphylococci and Bacteroides were high. These suggested that vaginitis may be caused by dysbiosis Loctobacilhs is the normal predominent flora in vagina and have antagonigtic action to pathogenic microbes. It is important for improving the vaginal mieroecosystem and good for health.

关 键 词：乳杆菌 阴道炎 菌群失调 

分 类 号：Q[生物学] R[医药卫生]