Significance of aberrant melanosomes in the diagnosis of malignant melanoma  

作　　者：高天文 刘荣卿 叶庆佾 

机构地区：[1]Department of Dermatology,Southwest Hospital,Third Military Medical College Chongqing 630038

出　　处：《Journal of Medical Colleges of PLA(China)》1993年第1期17-21,27,共6页中国人民解放军军医大学学报（英文版）

摘　　要：In order to clarify the significance of the aberrant melanosomes in thediagnosis of malignant melanoma,17 cases of malignant melanoma were studied with elec-tron microscopy,and 30 cases of nevus were studied likewise for comparison.Aberrantmelanosomes were present in 12 cases of pigmented and 2 cases of amelanotic malignantmelanoma.They were also found in 4 cases of congenital nevus.The findings suggest thatthe presence of aberrant melanosomes is of significance for the diagnosis of malignantmelanoma but this has been overemphasized.It is believed that the diagnosis of malignantmelanoma depends upon a comprehensive judgement of all the ultrastructural findings un-der electron microscopy.In order to clarify the significance of the aberrant melanosomes in the diagnosis of malignant melanoma,17 cases of malignant melanoma were studied with elec- tron microscopy,and 30 cases of nevus were studied likewise for comparison.Aberrant melanosomes were present in 12 cases of pigmented and 2 cases of amelanotic malignant melanoma.They were also found in 4 cases of congenital nevus.The findings suggest that the presence of aberrant melanosomes is of significance for the diagnosis of malignant melanoma but this has been overemphasized.It is believed that the diagnosis of malignant melanoma depends upon a comprehensive judgement of all the ultrastructural findings un- der electron microscopy.

关 键 词：melanoma ULTRASTRUCTURE ABERRANT MELANOSOME NEVUS PIGMENTED human 

分 类 号：R[医药卫生]