A Novel Fusion Protein Possessing Both Antiviral and pHSA-binding Activities Composed of Hepatitis B Virus Pre-S2 Peptide and Human α2a-interferon  

A Novel Fusion Protein Possessing Both Antiviral and pHSA-binding Activities Composed of Hepatitis B Virus Pre-S2 Peptide and Human α2a-interferon

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作  者:金冬雁 曾庆 周园 徐荣辉 李玉英 侯云德 

机构地区:[1]National Laboratory of Molecular Virology and Genetic Engineering, Chinese Academy of Preventive Medicine, Beijing 100052 PRC

出  处:《Chinese Science Bulletin》1993年第14期1216-1219,共4页

基  金:Project supported by grants from the State Commission of Science;Technology for the "863" Project for the Research and Development of Biotechnology.

摘  要:The human α-interferon(IFNα) is a group of proteins possessing activity to render cells resistant to viral infection. It is one of the most promising and well documented recombinant proteins used in biotherapy. A product of recombinant human α2a-interferon(IFN-α2a) first developed in our laboratory has been put into clinical trials upon the approval of the China National Committee for Drug Administration. Data show that

关 键 词:hepatitis B virus PRE-S2 PROTEIN HUMAN α2a-interferon fusion PROTEIN bifunctional molecule. 

分 类 号:N[自然科学总论]

 

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