Synthesis of an Antitumoral Diarylheptanoid Containing 1,3-Diol Functionality  

作　　者：张少敏 伍贻康 

机构地区：[1]State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2011年第12期2798-2802,共5页中国化学（英文版）

基　　金：Project supported by the National Basic Research Program of China （973 Program） （No. 2010CB833200）, the National Natural Science Foundation of China （Nos. 21032002, 20921091, 20672129, 20621062, 20772143） and the Chinese Academy of Sciences （＂Knowledge Innovation＂, Nn. KJCX2.YW.H08）

摘　　要：A bioactive derivative of a natural diarylheptanoid containing a 1,3-anti diol motif was synthesized with the oxygen-carrying stereogenic centers taken from an enantiopure epoxy chiral building block derived from inexpensive and readily available D-glucolactone.A bioactive derivative of a natural diarylheptanoid containing a 1,3-anti diol motif was synthesized with the oxygen-carrying stereogenic centers taken from an enantiopure epoxy chiral building block derived from inexpensive and readily available D-glucolactone.

关 键 词：natural products DIOL EPOXIDE phenol ETHER chiral building block 

分 类 号：TQ223.162[化学工程—有机化工] TS272[农业科学—茶叶生产加工]